Rare Fibroadenoma of the Anal Region

Christopher J. Buzas, Anju Gupta, Zong-ming Chen, J. Oxenberg
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Abstract

Introduction: Fibroadenomas are one of the most common benign breast lesions, however they have also been found on rare occasions elsewhere. These lesions usually arise from mammary-like glands (MLG) of the anogenital region which were first described by van der Putte. Methods: This case is about a 51-year-old female who presents with symptomatic hemorrhoids and a 5 cm nodular lesion external to the anal verge. These were removed and examined histo-pathologically. Results: Pathology revealed three hemorrhoidal specimens and the nodular lesion which was consistent with a fibroadenoma. Histologically, the nodular lesion demonstrated a benign process with ductal proliferation and estrogen receptors. Conclusions: Fibroadenomas in anatomic locations other than the breast are very uncommon. Other sites noted in prior case reports include gallbladder, prostate, arm, eyelid and anogenital region. Most of the anogenital lesions have been found on the vulva, with only six documented cases in the anal region, making this pathology exceedingly rare.
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肛门区罕见纤维腺瘤
纤维腺瘤是最常见的乳腺良性病变之一,但在其他地方也有罕见的发现。这些病变通常来自于肛门生殖器区域的乳腺样腺(MLG),由van der Putte首次描述。方法:本病例为51岁女性,有症状性痔疮,肛缘外有5cm结节状病变。将其切除并进行病理组织学检查。结果:病理显示三个痔疮标本,结节状病变与纤维腺瘤一致。组织学上,结节状病变表现为良性过程,伴导管增生和雌激素受体。结论:纤维腺瘤在除乳房以外的解剖部位是非常罕见的。先前病例报告中提到的其他部位包括胆囊、前列腺、手臂、眼睑和肛门生殖器区域。大多数的肛门生殖器病变都是在外阴发现的,只有六个记录的病例在肛门区域,使得这种病理非常罕见。
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