Premature termination of epidural analgesia—A prospective analysis to improve quality

F. Heid , T. Piepho , S. Stengel , A. Hofmann , J. Jage
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Abstract

Background and objective

Epidural analgesia (EA) is a gold-standard in post-operative pain control. Therefore, modern treatment concepts targeting early patient recovery regularly implement EA. Due to its increasing impact, EA should meet high quality standards in respect to application and maintenance. Though, daily practice often reveals EA-related problems, our investigation aimed to improve EA quality by assessing incidence and reasons of undeliberate, premature termination of post-operative EA.

Methods

In the first step all patients with post-operative EA were retrospectively studied covering a 6-month period (group 1). We analysed incidences and reasons of undeliberate termination of EA. Thereafter we modified our treatment protocols (preferential thoracic EA, continuous peripheral blocks, low concentrated local anaesthetic solutions, standardized co-medication). This was followed by a prospective analysis of all EA patients for another 6 months (group 2).

Results

777 patients were included (group 1 n = 400, group 2 n = 377). Undeliberate termination of post-operative EA was documented in 24.3% of group 1 patients (group 2: 14.1%; p < 0.05). In all patients, pain was the leading reason of premature termination (group 1: 52%; group 2: 68%), followed by motor block (group 1: 21%; group 2: 7.5%) and catheter dislocation (group 1: 10%; group 2: 16.7%).

Discussion

Modified treatment protocols reduced the rate of premature termination of EA from 24% to 14%. Particularly, we noted less motor impairment but still this rate is disappointing. The increasing rate of catheter dislocations underlines that a continuous analysis of all treatment aspects must be compulsatory.

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提前终止硬膜外镇痛——提高质量的前瞻性分析
背景与目的硬膜外镇痛(EA)是术后疼痛控制的金标准。因此,以患者早期康复为目标的现代治疗理念定期实施EA。由于其影响越来越大,EA在应用和维护方面应达到高质量标准。尽管日常实践中经常发现与EA相关的问题,但我们的研究旨在通过评估术后无意识、过早终止EA的发生率和原因来提高EA质量。方法第一步回顾性研究所有术后EA患者,为期6个月(第一组)。我们分析了无意识终止EA的发生率和原因。随后我们修改了治疗方案(优先胸腔EA,连续外周阻滞,低浓度局部麻醉溶液,标准化联合用药)。随后对所有EA患者进行了为期6个月的前瞻性分析(第二组)。结果纳入777例患者(第一组n = 400,第二组n = 377)。第1组患者中有24.3%的患者出现术后EA的非故意终止(第2组:14.1%;p & lt;0.05)。在所有患者中,疼痛是早产的主要原因(1组:52%;第2组:68%),其次是运动阻滞(第1组:21%;2组:7.5%)和导管脱位(1组:10%;第二组:16.7%)。改进的治疗方案将EA的过早终止率从24%降低到14%。特别是,我们注意到较少的运动损伤,但这个比率仍然令人失望。不断增加的导管脱位率强调,必须对所有治疗方面进行持续分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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