AstraZeneca Signs Two Deals to Reinforce its Pipeline After Development Setbacks

Heather Cartwright
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Abstract

After suffering development setbacks with regard to two of its late-stage drug candidates, AstraZeneca has signed separate deals with two Asian pharmaceutical companies to help bolster its sparse pipeline. In a deal potentially worth more than US$140 M, AstraZeneca has licensed rights from Hutchison MediPharma to co-develop and commercialise volitinib, a preclinical c-Met receptor tyrosine kinase inhibitor being developed for cancer. The company has also obtained an option to acquire the type 2 diabetes assets of Astellas Pharma’s Prosidion subsidiary, Phase II PSN821 and preclinical-stage PSN842.
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阿斯利康在研发受挫后签署两项协议加强产品线
阿斯利康(AstraZeneca)在两款后期候选药物的研发遭遇挫折后,已与两家亚洲制药公司分别签署了协议,以帮助充实其稀少的研发渠道。在一项潜在价值超过1.4亿美元的交易中,阿斯利康从和黄医药获得了共同开发和商业化volitinib的权利,volitinib是一种临床前c-Met受体酪氨酸激酶抑制剂,正在开发用于癌症。该公司还获得了收购安斯泰来子公司Prosidion II期PSN821和临床前PSN842 2型糖尿病资产的选择权。
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