Minimizing cotton ball retention in neurological procedures.

IF 42.5 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Cell Pub Date : 2020-04-01 Epub Date: 2020-07-27 DOI:10.1115/dmd2020-9042
Raphael Bechtold, Benjamin Garlow, Renee Liu, Arushi Tandon, Alexandra Szewc, William Zhu, Olivia Musmanno, Noah Gorelick, Ian Suk, Judy Huang, Henry Brem, Amir Manbachi, George Coles
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Abstract

Neurosurgical operations are long and intensive medical procedures, during which the surgeon must constantly have an unobscured view of the brain in order to be able to properly operate, and thus must use a variety of tools to clear obstructions (like blood and fluid) from the operating area. Currently, cotton balls are the most versatile and effective option to accomplish this as they absorb fluids, are soft enough to safely manipulate the brain, act as a barrier between other tools and the brain, and function as a spacer to keep anatomies of the brain open and visible during the operation. While cotton balls allow neurosurgeons to effectively improve visibility of the operating area, they may also be accidentally left in the brain upon completion of the surgery. This can lead to a wide range of post-operative risks including dangerous immune responses, additional medical care or surgical operations, and even death. This project seeks to develop a unique medical device that utilizes ultrasound technology in order to minimize cotton retention after neurosurgical procedures in order to reduce undesired post-operative risks, and maximize visibility.

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在神经外科手术中尽量减少棉球滞留。
神经外科手术是一项漫长而紧张的医疗程序,在手术过程中,外科医生必须始终保持对大脑的无障碍观察,才能正确地进行手术,因此必须使用各种工具清除手术区的障碍物(如血液和液体)。目前,棉球是实现这一目的最通用、最有效的选择,因为棉球能吸收液体,柔软度足以安全地操作大脑,是其他工具和大脑之间的屏障,还能在手术过程中充当保持大脑解剖结构开放和可见的间隔物。虽然棉球能让神经外科医生有效提高手术区域的可见度,但也可能在手术完成后意外留在脑内。这可能导致各种术后风险,包括危险的免疫反应、额外的医疗护理或外科手术,甚至死亡。本项目旨在开发一种独特的医疗设备,利用超声波技术最大限度地减少神经外科手术后的棉花残留,从而降低术后风险,并最大限度地提高可见度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cell
Cell 生物-生化与分子生物学
CiteScore
110.00
自引率
0.80%
发文量
396
审稿时长
2 months
期刊介绍: Cells is an international, peer-reviewed, open access journal that focuses on cell biology, molecular biology, and biophysics. It is affiliated with several societies, including the Spanish Society for Biochemistry and Molecular Biology (SEBBM), Nordic Autophagy Society (NAS), Spanish Society of Hematology and Hemotherapy (SEHH), and Society for Regenerative Medicine (Russian Federation) (RPO). The journal publishes research findings of significant importance in various areas of experimental biology, such as cell biology, molecular biology, neuroscience, immunology, virology, microbiology, cancer, human genetics, systems biology, signaling, and disease mechanisms and therapeutics. The primary criterion for considering papers is whether the results contribute to significant conceptual advances or raise thought-provoking questions and hypotheses related to interesting and important biological inquiries. In addition to primary research articles presented in four formats, Cells also features review and opinion articles in its "leading edge" section, discussing recent research advancements and topics of interest to its wide readership.
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