Comparative Dissolution Study of Different Brands of Amoxicillin Trihydrate Capsules Available in Bangladesh

N. Huda, Y. Jhanker, A. Shahid-ud-Daula, Most. Nazma Parvin, Shammy Sarwar
{"title":"Comparative Dissolution Study of Different Brands of Amoxicillin Trihydrate Capsules Available in Bangladesh","authors":"N. Huda, Y. Jhanker, A. Shahid-ud-Daula, Most. Nazma Parvin, Shammy Sarwar","doi":"10.3329/SJPS.V2I2.5827","DOIUrl":null,"url":null,"abstract":"Commercially available twenty national and four multinational brands of Amoxicillin Trihydrate capsules were studied  in water  for 60 minutes using USP reference dissolution apparatus. All, except  two national brands (Code: NB-8 and NB-15); complied with  the USP  in vitro dissolution specification  for drug release (not  less than 80% of the labelled amount of amoxicillin trihydrate should be dissolved in 60 minutes). Drug releases from those two brands were 75% and 67% respectively within the specified time period. Key words: In vitro Dissolution; Market preparations; Amoxicillin Trihydrate; Capsule; National Brand; Multinational Brand. DOI: 10.3329/sjps.v2i2.5827 Stamford Journal of Pharmaceutical Sciences Vol.2(2) 2009: 72-75","PeriodicalId":21823,"journal":{"name":"Stamford Journal of Pharmaceutical Sciences","volume":"54 1","pages":"72-75"},"PeriodicalIF":0.0000,"publicationDate":"2010-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stamford Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/SJPS.V2I2.5827","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

Abstract

Commercially available twenty national and four multinational brands of Amoxicillin Trihydrate capsules were studied  in water  for 60 minutes using USP reference dissolution apparatus. All, except  two national brands (Code: NB-8 and NB-15); complied with  the USP  in vitro dissolution specification  for drug release (not  less than 80% of the labelled amount of amoxicillin trihydrate should be dissolved in 60 minutes). Drug releases from those two brands were 75% and 67% respectively within the specified time period. Key words: In vitro Dissolution; Market preparations; Amoxicillin Trihydrate; Capsule; National Brand; Multinational Brand. DOI: 10.3329/sjps.v2i2.5827 Stamford Journal of Pharmaceutical Sciences Vol.2(2) 2009: 72-75
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
孟加拉国不同品牌三水合阿莫西林胶囊溶出度比较研究
用USP标准溶出度仪对市售的20个国家品牌和4个跨国品牌的三水合阿莫西林胶囊进行了60分钟的水溶出度研究。除两个国家品牌(代码:NB-8和NB-15)外;符合USP体外释放度标准(不少于三水阿莫西林标记量的80%应在60分钟内溶出)。两个品牌在规定时间内的释药率分别为75%和67%。关键词:体外溶出度;市场准备工作;阿莫西林三水合物;胶囊;国家品牌;跨国品牌。DOI: 10.3329/sjps.v2i2.5827斯坦福制药科学杂志Vol.2(2) 2009: 72-75
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Dissolution study of Spironolactone by using solid dispersion technique Toxicological studies of Darvyadi Kvatha Curna using albino rats In-vitro phytochemical and anthelmintic activity of Cocculus hirsutus Linn. and Rumex dentatus Linn. Risk factors and trends of common cancers in Bangladesh: Outcome of hospital based case control survey conducted in Dhaka city, Bangladesh Preparation and comparative evaluation of liquisolid compacts and solid dispersions of Valsartan
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1