Systematic Review: Vulnerability of Metabolic Syndrome in COVID-19

D. Dhawan, Shailja Sharma
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Abstract

SARS-CoV-2 infection has become a widely spread disease around the world causing rapid hospitalization and death, especially in people with metabolic syndrome. There is very limited literature that goes to present the clinical implications and management of metabolic syndrome in this pandemic. Hence an attempt has been made towards meeting this end. A literature review has been done extracting articles from scopus database following PRISMA guidelines. The manuscripts were studied to identify articles that report metabolic syndrome and its components in COVID-19 infection. A total of 25 manuscripts were included in this systematic review. These studies report systematic inflammation and organ damage in metabolic syndrome that has up regulated SARS-CoV-2 infection. Various treatment strategies have also been suggested and hypothesized. The results of this analysis indicate that patients suffering from metabolic syndrome are vulnerable to COVID-19 owing a sequence of complications.
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系统评价:代谢综合征在COVID-19中的易感性
SARS-CoV-2感染已成为一种在世界各地广泛传播的疾病,导致快速住院和死亡,特别是在代谢综合征患者中。在这次大流行中,关于代谢综合征的临床意义和管理的文献非常有限。因此,为达到这一目的作出了努力。根据PRISMA指南从scopus数据库中提取文章进行文献综述。对这些手稿进行了研究,以确定报告COVID-19感染中代谢综合征及其组成部分的文章。本系统综述共收录了25篇论文。这些研究报告了代谢综合征的系统性炎症和器官损伤,这些代谢综合征已经上调了SARS-CoV-2感染。各种治疗策略也被提出和假设。这一分析结果表明,由于一系列并发症,患有代谢综合征的患者很容易感染COVID-19。
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