Effects of Heavy Metal Toxicity on Anxiety Disorder

Mfem Cc, Seriki Sa, Oyama Se
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Abstract

Background: Several heavy metals are found naturally in the earth crust and are exploited for various industrial and economic purposes. Among these heavy metals, a few have impact on the human body. Though some of these metals only have effect on human physiology in high doses, others such as cadmium, mercury, lead, chromium, silver, and arsenic have delirious effects in the body even in minute quantities, causing acute and chronic toxicities in human. Anxiety is a common psychiatric disorder among men and women. Occasional anxiety may be a normal a part of life. However, people with anxiety disorders frequently have intense, excessive and persistent worry and fear about everyday situations. Often, anxiety disorders involve repeated episodes of sudden feelings of intense anxiety and fear or terror that reach a peak within minutes (panic attacks). This study examined a major environmental risk factor of anxiety disorder and how the adverse impact of anxiety disorder could be ameliorated using zinc and vitamin E. Methods: Animals used for the researched were grouped into four. Group 1 represents control group; Group 2 represents animals exposed a heavy metal (CaCl2); Group 3 represents animals exposed to CaCl2 and then treated with zinc; and Group 4 represents animals exposed to CaCl2 and then treated vit E. Results: Results showed that exposure to heavy metals (CaCl2 in particular) causes severe anxiety disorders. Results also showed zinc and vit E have the capacity to ameliorate anxiety disorder caused by heavy metals. Conclusion: The human body should be adequately protected as man interacts with heavy metals to prevent anxiety disorder, and where a patient becomes a victim of the disorder, zinc and vit E could be used to manage the case.
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重金属毒性对焦虑症的影响
背景:几种重金属在地壳中自然存在,并被用于各种工业和经济目的。在这些重金属中,有少数对人体有影响。虽然其中一些金属只有在高剂量时才对人体生理产生影响,但其他金属如镉、汞、铅、铬、银和砷,即使是微量也会对人体产生精神错乱的作用,对人体造成急性和慢性毒性。焦虑是男性和女性中常见的精神疾病。偶尔的焦虑可能是生活中正常的一部分。然而,患有焦虑症的人经常对日常情况有强烈、过度和持续的担忧和恐惧。通常,焦虑障碍包括反复发作的突然强烈焦虑和恐惧或恐怖的感觉,并在几分钟内达到顶峰(惊恐发作)。本研究探讨了焦虑障碍的一个主要环境风险因素,以及如何通过锌和维生素e来改善焦虑障碍的不利影响。第1组为对照组;第二组为接触重金属(CaCl2)的动物;第3组为先暴露于CaCl2后再给予锌处理的动物;第4组是暴露于CaCl2然后进行维生素e治疗的动物。结果表明,暴露于重金属(特别是CaCl2)会导致严重的焦虑症。结果还表明锌和维生素E有改善重金属引起的焦虑障碍的能力。结论:当人体与重金属相互作用时,应充分保护人体以预防焦虑症,当患者成为焦虑症的受害者时,锌和维生素E可用于管理病例。
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