Total Humeral Replacement with Biarticular Prosthesis after Chondrosarcoma Wide Excision Functional Aspects of Limb Preservation

P. Serrano
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Abstract

The humerus is commonly affected by primary malignant bone tumors that may require wide surgical “en bloc” excision, when staging is negative [1,2]. When major nerves and vessels are not involved, limb salvage surgery becomes the mainstay treatment [3,4]. Total humerus replacement (THR), with shoulder and elbow arthroplasty, is a rarely performed surgery, but is the only reconstructive solution, providing partial aesthetic and functional preservation, when total humerus resection is required ¬[5-8]. The literature regarding functional and oncological outcomes for this procedure is limited, but published results are overall acceptable [6,9,10]. Compared to ablative surgery, limb preservation provides better functional outcomes with no difference in overall patient survival [11,12].
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软骨肉瘤广泛切除后全肱骨置换术及双关节假体对肢体保留功能的影响
肱骨常受原发性恶性骨肿瘤的影响,当分期为阴性时,可能需要广泛的手术“整体”切除[1,2]。当不累及主要神经和血管时,保肢手术成为主要的治疗方法[3,4]。全肱骨置换术(THR)与肩关节和肘关节置换术是一种很少进行的手术,但当需要全肱骨切除术时,它是唯一的重建解决方案,可提供部分美观和功能保留[5-8]。关于该手术的功能和肿瘤预后的文献有限,但已发表的结果总体上是可以接受的[6,9,10]。与消融手术相比,肢体保留提供了更好的功能结果,总体患者生存率无差异[11,12]。
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