The Clinical and Social Economic Profile of Patients Diagnosed with COVID-19 at Likuni Mission Hospital, Malawi.

Adriano Lubanga, Alfred Lipenga, V. Mwapasa, Gift Kanyinji, Darlington Ndlovu, Tuntufye Sichinga, George Mwenye-Phiri, Louis Ng’oma, Elled Mwenyekonde, Donghyun Jeon, Seok Han, Kaylin Choe, J. Seung, Justin Kong, T. Nyirenda
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Abstract

Background: The COVID-19 pandemic has caused devastating effects on the world since its discovery in the city of Wuhan in 2019. It has claimed millions of lives and has significantly affected the economies of the world. However, the characteristics of affected populations in poorest settings in Africa are not clearly known. Aims and Objectives: The study was undertaken to evaluate common clinical presentations of patients diagnosed with COVID-19, asses the socio-economic and demographic profiles and analyze the clinical course, and comorbidities of COVID-19 positive patients at Likuni mission hospital, central region of Malawi. Methods: This was a cross sectional study, however we looked at retrospective data from for all patients diagnosed from January 2021 to January 2022. Results: Patients were predominantly female (65%), less than 40 years, without any known comorbidity and had at least 3 symptoms before being diagnosed. The most common symptoms were fever, cough, chest pains, headache, shortness of breath, and general body weakness. A significantly higher population were from low social economic status (p<0.05). Over 95% of the population suffered minor ailment and did not need hospitalization and advanced life support. All patients that required hospitalization were above the age of 60 and the results were statistically significant (p<0.05). More than 90% of the cases were locally spread and did not have traceable positive contact. Conclusion: The diversity of clinical and epidemiological characteristic of patients diagnosed with COVID-19 across gender, socio-economic status, age group and occupation is extremely important. Our results provides an understanding of the characteristics of patients in a poor setting like Malawi and will inform policy makers at local hospitals and district levels including researchers and the ministry of health.
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马拉维利库尼教会医院COVID-19患者的临床和社会经济状况
背景:新冠肺炎疫情自2019年在武汉市被发现以来,对世界造成了毁灭性影响。它夺去了数百万人的生命,并对世界经济产生了重大影响。然而,非洲最贫穷环境中受影响人口的特点尚不清楚。目的和目的:本研究在马拉维中部地区的Likuni教会医院开展,旨在评估COVID-19确诊患者的常见临床表现,评估社会经济和人口统计学特征,并分析COVID-19阳性患者的临床病程和合并症。方法:这是一项横断面研究,但我们查看了从2021年1月到2022年1月诊断的所有患者的回顾性数据。结果:患者以女性为主(65%),年龄小于40岁,无任何已知合并症,确诊前至少有3种症状。最常见的症状是发烧、咳嗽、胸痛、头痛、呼吸急促和全身无力。社会经济地位低下的人群显著高于其他人群(p<0.05)。95%以上的人口患有轻微疾病,不需要住院治疗和高级生命支持。需要住院治疗的患者年龄均在60岁以上,差异有统计学意义(p<0.05)。90%以上的病例是本地传播的,没有可追踪的阳性接触。结论:新型冠状病毒肺炎确诊患者的临床和流行病学特征在性别、社会经济地位、年龄组和职业之间的差异极为重要。我们的研究结果提供了对马拉维等贫困地区患者特征的理解,并将为当地医院和地区层面的决策者(包括研究人员和卫生部)提供信息。
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