Effect of High Fat Diet and Endurance Training on the Gene Expression of Sarco/Endoplasmic Reticulum ATPase2 (SERCA2) and Ryanodine Receptor2 (RYR2) under Near-Thermoneutrality in Inguinal Adipose Tissue of Mice
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Abstract
showed that the relative gene expression of SERCA2a, SERCA2b, and RYR2 were not significantly affected by HFD, ET, and HFD-ET (P>0.05). Discussion & Conclusion: The HFD and ET did not change the regulatory proteins of the futile-calcium-cycle under near-thermoneutrality in the beige adipose tissue. Therefore, it was speculated that the non-shivering thermogenesis that is induced by these conditions might occur independently of futile-cycle-calcium.
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