Ultrasonographic detection of hepatic tumors in experimental model of chemical induced hepatocarcinogenesis in Wistar Albino rats

Abstract

In the present study, hepatic tumors were chemically induced in male Wistar Albino rats with Diethylnitrosamine. Hepatic ultrasonography was performed to detect the development of hepatic tumors clinically at the end of treatment period. In sonography, the presence of tumor nodules was appreciated as the indistinct hepatic borders and circumscribed varied echogenicity with distinct hyperechoic borders in the affected portion of liver in contrast to the liver of negative control rats which showed distinct borders, homogenous parenchyma and medium echogenicity.