Spectroscopic Analysis and ADME Studies of Phytochemicals in Methanolic Leaves Extract of Sonneratia apetala Buch.-Ham

Nishant Nandkhile, Sachin Vanpure, Prathmesh Khetmalis, R. Bhondwe
{"title":"Spectroscopic Analysis and ADME Studies of Phytochemicals in Methanolic Leaves Extract of Sonneratia apetala Buch.-Ham","authors":"Nishant Nandkhile, Sachin Vanpure, Prathmesh Khetmalis, R. Bhondwe","doi":"10.52711/0975-4385.2022.00029","DOIUrl":null,"url":null,"abstract":"The plants are enormous source of medicinally important ingredients. The separation of active plants compounds leads to discovery of many drugs derived directly from plants. In the current study, The HPLC analysis is carried for the methanolic extracts of gives different peaks at 254 nm, it may be alcoholic compound. The FTIR spectrum confirmed the presence of alcohol, alkanes, carboxylic acid, aromatics, esters and ethers in methanolic extract of Sonneratia apetala. UV-Visible profile showed different peaks ranging from 200-800 nm with different absorption respectively. In silico study, especially physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug likeness and medicinal chemistry performed by using the Swiss ADME online tool.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"337 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Journal of Pharmacognosy and Phytochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/0975-4385.2022.00029","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

Abstract

The plants are enormous source of medicinally important ingredients. The separation of active plants compounds leads to discovery of many drugs derived directly from plants. In the current study, The HPLC analysis is carried for the methanolic extracts of gives different peaks at 254 nm, it may be alcoholic compound. The FTIR spectrum confirmed the presence of alcohol, alkanes, carboxylic acid, aromatics, esters and ethers in methanolic extract of Sonneratia apetala. UV-Visible profile showed different peaks ranging from 200-800 nm with different absorption respectively. In silico study, especially physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug likeness and medicinal chemistry performed by using the Swiss ADME online tool.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
无瓣海桑甲醇叶提取物中植物化学物质的光谱分析及ADME研究
这些植物是重要药用成分的巨大来源。活性植物化合物的分离导致许多直接从植物中提取的药物的发现。本研究对其甲醇提取物进行了高效液相色谱分析,在254 nm处出现不同的峰,可能为醇性化合物。红外光谱分析证实无花瓣海桑甲醇提取物中存在醇类、烷烃类、羧酸类、芳烃类、酯类和醚类化合物。紫外-可见光谱在200 ~ 800 nm范围内呈现不同的吸收峰。通过使用瑞士ADME在线工具进行硅片研究,特别是物理化学性质,亲脂性,水溶性,药代动力学,药物相似性和药物化学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
A Review on Various Phytochemical Structure Significance of Terminalia arjuna Botanical Study of Berberis vulgaris L of Family Berberidaceae: A Review An Overview on Bioactive Phytochemical Investigation of Tinospora cordifolia (Guduchi) Physico and Phyto-chemical Evaluation of Seeds and their Extracted Crude Oil’s Characteristic of a Nutritionally important plant Daucus carota Linn Antimicrobial Activity of Caesalpinia pulcherrima (L.) Leaves Extracts against Food Borne Pathogenic and Spoilage Microorganisms
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1