Nishant Nandkhile, Sachin Vanpure, Prathmesh Khetmalis, R. Bhondwe
{"title":"Spectroscopic Analysis and ADME Studies of Phytochemicals in Methanolic Leaves Extract of Sonneratia apetala Buch.-Ham","authors":"Nishant Nandkhile, Sachin Vanpure, Prathmesh Khetmalis, R. Bhondwe","doi":"10.52711/0975-4385.2022.00029","DOIUrl":null,"url":null,"abstract":"The plants are enormous source of medicinally important ingredients. The separation of active plants compounds leads to discovery of many drugs derived directly from plants. In the current study, The HPLC analysis is carried for the methanolic extracts of gives different peaks at 254 nm, it may be alcoholic compound. The FTIR spectrum confirmed the presence of alcohol, alkanes, carboxylic acid, aromatics, esters and ethers in methanolic extract of Sonneratia apetala. UV-Visible profile showed different peaks ranging from 200-800 nm with different absorption respectively. In silico study, especially physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug likeness and medicinal chemistry performed by using the Swiss ADME online tool.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"337 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Journal of Pharmacognosy and Phytochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/0975-4385.2022.00029","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
The plants are enormous source of medicinally important ingredients. The separation of active plants compounds leads to discovery of many drugs derived directly from plants. In the current study, The HPLC analysis is carried for the methanolic extracts of gives different peaks at 254 nm, it may be alcoholic compound. The FTIR spectrum confirmed the presence of alcohol, alkanes, carboxylic acid, aromatics, esters and ethers in methanolic extract of Sonneratia apetala. UV-Visible profile showed different peaks ranging from 200-800 nm with different absorption respectively. In silico study, especially physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug likeness and medicinal chemistry performed by using the Swiss ADME online tool.