Trasplante de médula ósea para el tratamiento de la enfermedad de Crohn refractaria

Abstract

Crohn's disease affects a part of the young population and has a strong impact on quality of life. Its etiology is unknown and existing drugs are not curative. In addition, a significant proportion of patients present intolerance, refractoriness, or loss of response to available medical therapies, and surgery is not a good option due to the extent or location of the disease. In recent years, a thorough investigation into new ways of dealing with refractory Crohn's disease is being developed, with new medical therapeutic targets but also cell therapy, including stem cell transplant, with encouraging results.