Subarachnoid Hemorrhage: A Neurological Emergency

M. Venti, Monica Acciarresi, G. Agnelli
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引用次数: 2

Abstract

Subarachnoid hemorrhage (SAH) accounts for 5% of all strokes but its burden is relevant due to high mortality, high disability and remarkable incidence in the young. The rupture of an intracranial aneurysm is responsible for about 85% of SAHs; 10% are represented by non-aneurysmal conditions; 5% are represented by other medical conditions such as inflammatory or non-inflammatory lesions of cerebral artery, coagulopathy, neoplasms or drug abuse. The clinical presentation of a subarachnoid hemorrhage can be extremely variable ranging from nearly asymptomaticity to sudden death. Neuroimaging represent the first level instrumental investigation. In case of clinical suspect of SAH and negative neuroimaging, cerebrospinal fluid (CSF) examination is required. Following the diagnosis of SAH, determining cause and localization of bleeding is mandatory; digital catheter angiography is the gold standard. Rebleeding is the most frequent and severe complication of SAH. The aneurysm exclusion is the most effective treatment for preventing rebleeding. Endovascular occlusion of the aneurysm with coils has been shown to be associated with better short- and long-term outcomes than surgical clipping in select patients.
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蛛网膜下腔出血:神经急症
蛛网膜下腔出血(SAH)占所有中风的5%,但由于其高死亡率、高致残率和显著的年轻人发病率,其负担是相关的。颅内动脉瘤破裂约占SAHs的85%;10%为非动脉瘤性疾病;5%为其他疾病,如脑动脉炎症性或非炎症性病变、凝血功能障碍、肿瘤或药物滥用。蛛网膜下腔出血的临床表现可以是非常多变的,从几乎无症状到猝死。神经影像学是第一层次的仪器检查。临床怀疑为SAH且神经影像学阴性时,需行脑脊液检查。诊断SAH后,确定出血的原因和定位是必须的;数字导管血管造影是金标准。再出血是SAH最常见和最严重的并发症。动脉瘤排除术是预防再出血最有效的治疗方法。在一些特定的患者中,血管内动脉瘤线圈闭塞比手术夹闭具有更好的短期和长期预后。
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