The impact of apheresis on iron stores

Vanessa J. Martlew MB, MRCP, MRCPath , H.M. Waters MSc, FIMLS , J.E. Howarth BSc, FIMLS, DMLM
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引用次数: 1

Abstract

Monthly plasmapheresis of volunteer donors was introduced at the Manchester Apheresis Centre late in 1985. Serum ferritin was measured at the outset and after 12 months regular donation to monitor iron stores. In a cohort of 100 male and 86 female blood donors it was found that both groups had mean serum ferritins lower than non-donor controls. A year after conversion to monthly plasma donation the female donors were found to increase mean serum ferritin almost to that of the control subjects while a much smaller rise was observed in their male counterparts.

It was concluded that plasmapheresis is conservative of iron stores, and the benefits are apparent earlier in females.

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离心对铁储量的影响
1985年晚些时候,曼彻斯特血浆分离中心开始对志愿捐献者进行每月一次的血浆分离。在开始和12个月定期捐献后测定血清铁蛋白以监测铁储量。在一个由100名男性和86名女性献血者组成的队列中,发现两组的平均血清铁蛋白都低于非献血者对照组。在转为每月捐献血浆一年后,研究人员发现,女性捐献者的平均血清铁蛋白水平几乎与对照组持平,而男性捐献者的平均血清铁蛋白水平上升幅度要小得多。由此可见,血浆置换对铁的储存是保守的,其益处在女性中较早显现。
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Author index Editorial Board Effects of plasticizers on red blood cells and platelets during storage Changes in plasma coagulation factors during blood storage Studies on contact phase and platelet activation during thrombopheresis in donors. Preliminary results of a comparison between continuous and intermittent flow systems
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