[Quantitative Measurement of 123I-MIBG Myocardial Scintigraphy Using Semiconductor Detector Gamma Camera].

Abstract

In late years, in 123I-Metaiodobenzylguanidine (123I-MIBG), it was established in cardiac sympathetic nerve functional disorder as objective evaluable inspection, and the heart/mediastinum ratio (the H/M ratio) in the planar image and fixed-quantity indexes including wash-out rate were unified by Nakajima and others. The H/M ratio brings the information that is useful for a heart failure disease severity evaluation, a prognosis, a therapeutic effect judgment. On the other hand, the issue of difference revision between the institutions with the semiconductor γ camera which has begun to be introduced in an own country remains. We developed the H/M ratio revision method in a semiconductor γ camera and an Anger scintillation camera this time and inspected it. I was able to be standardized using the H/M correction function that I obtained in this study.