A Review on: Phytoconstituents, Traditional and Medicinal uses of Taraxacum offinale (Dandelion)

Umair Akhtar, Anjali M. Wankhade, Jugalkishor V. Vyas, Vivek V. Paithankar
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Abstract

Since 5000 BC, medicinal plants have been used in India as part of the Ayurvedic medical system. Medical professionals frequently use herbal remedies. Taraxacum officinale, commonly called dandelion, is a perennial plant belonging to the family Asteraceae. It is also known as wet-a-bed, lion’s tooth, priest’s crown, blowball, milk gowan, wild endive, white endive, puffball, and Irish daisy. Long and upright flowering stalks with a single terminal inflorescence are present. It has numerous medicinal properties due to phytochemicals found in the plant's flower, leaf, stem, and roots. Sesquiterpenes found in dandelion root extracts. The root also includes a number of phenolic substances. The two sesquiterpenes taraxinic acid b-Dglucopyranoside and 11, 13-dihydrotaraxinic acid b-Dglucopyranoside An extract of combined dandelion leaves and flowers has been found to contain a number of flavonoid glycosides. Dandelion roots and leaves have historically been used to treat liver issues. Additionally, Native Americans used dandelion to treat heartburn, swelling, skin issues, kidney disease, and upset stomach. Research has been conducted to back up the descriptions of taraxacum that have been made so far. Up to doses of 10 g/kg (per oral) and 4 g/kg (intraperitoneal) of dried drug -per kilogramme body weight- in rats and mice, ethanolic extracts demonstrated very low toxicity.
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蒲公英(Taraxacum offinale)植物成分、传统及药用研究进展
自公元前5000年以来,药用植物已经在印度被用作阿育吠陀医疗系统的一部分。医疗专业人员经常使用草药治疗。蒲公英,俗称蒲公英,是一种多年生植物,属于菊科。它也被称为wet-a-bed,狮子的牙齿,牧师的皇冠,blowball, milk gowan,野生菊苣,白菊苣,puffball和爱尔兰雏菊。具有单顶生花序的长而直立的花柄。由于在植物的花、叶、茎和根中发现的植物化学物质,它具有许多药用特性。蒲公英根提取物中的倍半萜素。根中还含有许多酚类物质。两种倍半萜蒲公英酸b-Dglucopyranoside和11,13 -二氢蒲公英酸b-Dglucopyranoside是蒲公英叶和花的提取物,已被发现含有许多类黄酮苷。蒲公英的根和叶历来被用来治疗肝脏问题。此外,美洲原住民用蒲公英治疗胃灼热、肿胀、皮肤问题、肾脏疾病和胃部不适。已经进行了研究来支持迄今为止对蒲公英的描述。在大鼠和小鼠中,高达每公斤体重10克/公斤(每次口服)和4克/公斤(腹腔注射)的干燥药物剂量,乙醇提取物显示出非常低的毒性。
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