Assessing Alterations in Food Preference as a Mechanism Contributing to Weight Loss After Gastric Bypass Surgery

A. Melvin, C. L. le Roux, N. Docherty
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Abstract

Roux-en-Y gastric bypass (RYGB) surgery is a very successful option for the management of obesity, and our understanding of how this intervention mediates sustained weight loss continues to grow. Controversy exists regarding whether bariatric surgical procedures such as RYGB may modulate food preferences of individuals, in particular, reducing appetitive and consummatory behaviour toward dietary fat. Herein, we summarise the evidence base regarding changes in food and macronutrient preference following RYGB surgery and discuss the challenges faced by investigators attempting to resolve whether this is a causal phenomenon in RYGB-induced weight loss and whether its development reflects a conditioned response.
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评估食物偏好的改变作为胃旁路手术后体重减轻的机制
Roux-en-Y胃旁路手术(RYGB)是治疗肥胖的一个非常成功的选择,我们对这种干预如何介导持续减肥的理解在不断增长。关于诸如RYGB之类的减肥外科手术是否可以调节个体的食物偏好,特别是减少对膳食脂肪的食欲和消费行为,存在争议。在此,我们总结了RYGB手术后食物和宏量营养素偏好变化的证据基础,并讨论了研究人员在试图解决这是否是RYGB引起的体重减轻的因果现象以及其发展是否反映了条件反应时所面临的挑战。
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