Ceruminous gland adenoma of the external auditory canal: A case report

K. Koulia, A. Tsavari, D. Myoteri, A. Zisi, E. Skafida, X. Grammatoglou, T. Vasilakaki
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Abstract

Ceruminous gland adenoma is a very rare bening neoplasm of the external auditory canal. This tumour composed of the ceruminous gland cell (modified apocrine sweat glands). We report a case of a 39 year old man who presented with signs of scratching at the left ear. Otoscopic examination revealed an exophytic skin covered smooth nodule 1,2 cm in greatest dimension on the posterior wall of the external auditory canal. Local wide resection of the lesion was performed. Microscopically the lesion composed of oxyphil glands and small cysts in a hyalinized stroma. The glandular epithelium was bilayered. In the immunohistochemical study the luminal cells were strongly positive with CK7 while the basal cells were highlighted with CK5/6, p63 and S100 protein. The diagnosis was ceruminous gland adenoma. Three years later there was no evidence of recurrence. Complete surgical excision is therefore the treatment of choise.
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外耳道耵聍腺瘤1例
摘要耵聍腺瘤是一种非常罕见的外耳道良性肿瘤。该肿瘤由耵聍腺细胞(修饰的大汗腺)组成。我们报告一个39岁的男子谁提出的迹象抓挠在左耳。耳镜检查发现外耳道后壁有一个外生皮肤覆盖的光滑结节,最大尺寸为1.2厘米。局部广泛切除病变。镜下病变由嗜氧腺和透明基质中的小囊肿组成。腺上皮呈双层结构。在免疫组化研究中,管腔细胞强烈表达CK7,基底细胞则表达CK5/6、p63和S100蛋白。诊断为耵聍腺瘤。三年后没有复发的迹象。因此,完全手术切除是治疗的选择。
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