Comparative Study on Antioxidant Activity and Cytotoxicity of Defatted Kernels of Mango (Mangifera indica) and Wild Mango (Irvingia gabonensis and Irvingia wombolu)

Omada, A. Akogwu, Arogba
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Abstract

Defatted kernel powder of mango (Mangifera indica) and wild mango (Irvingia gabonensis and Irvingia wombolu) were analysed for their in-vitro antioxidant activity and cytotoxicity. Dry matter content of the three kernel types were in the range of 93 to 95%. On defatting, the percentage oil yield of the Irvingia varieties were similar and 200% higher than that of Mangifera indica. The antioxidant activity using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) technique showed that the two Irvingia varieties (DIGK and DIWK) had similar IC50 (p>0.05) but significantly higher than that of Mangifera indica kernel (DMIK) (p<0.05). Likewise, results from the Ferric Reducing Antioxidant Power (FRAP) technique and Cytotoxicity assay confirmed the higher potency of DMIK over the Irvingia kernels.
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芒果(Mangifera indica)与野生芒果(Irvingia gabonensis和Irvingia wombolu)脱脂果仁的抗氧化活性和细胞毒性比较研究
对芒果(Mangifera indica)和野生芒果(Irvingia gabonensis和Irvingia wombolu)脱脂仁粉的体外抗氧化活性和细胞毒性进行了分析。3种核型的干物质含量在93% ~ 95%之间。在脱脂方面,欧文尼亚品种的百分比出油率与芒果相似,高出200%。采用2,2 -二苯基-1-苦酰基肼(DPPH)法测定2个Irvingia品种(DIGK和DIWK)的抗氧化活性,其IC50值相近(p>0.05),但显著高于Mangifera indica kernel (DMIK) (p<0.05)。同样,铁还原抗氧化能力(FRAP)技术和细胞毒性试验的结果证实了DMIK对Irvingia籽粒的更高效力。
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