Laura A. Sordillo, P. Sordillo, Lin Zhang, R. Alfano
{"title":"Tryptophan and kynurenines in neurodegenerative disease","authors":"Laura A. Sordillo, P. Sordillo, Lin Zhang, R. Alfano","doi":"10.1364/boda.2019.jt4a.8","DOIUrl":null,"url":null,"abstract":"There is mounting evidence that there exists a connection between abnormal tryptophan metabolism and neurodegenerative diseases. The relationship between tryptophan and kynurenines in 48 age-matched normal and Alzheimer’s disease human brain tissues was investigated using label-free fluorescence spectroscopy.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"262 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/boda.2019.jt4a.8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
There is mounting evidence that there exists a connection between abnormal tryptophan metabolism and neurodegenerative diseases. The relationship between tryptophan and kynurenines in 48 age-matched normal and Alzheimer’s disease human brain tissues was investigated using label-free fluorescence spectroscopy.
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