Evaluation of the Appropriateness of Thyroid Fine-Needle Aspiration

Lairce Cristina Ribeiro Brito, Iara Beatriz De Carvalho Botêlho, Lanna Matos Silva Fernandes, Nayze Lucena Sangreman Aldeman, Uziel Nunes Silva
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Abstract

This study aims to perform an integrative literature review on FNAB of the thyroid and its current contributions facing thyroid nodules, as an important diagnostic tool to eliminate early thyroid cancer, a recurrent pathology in offices. Regarding the methods, because this is an integrative review of literature, through a descriptive study, we used databases such as Medical Literature Analysis and Retrieval System Online (Medline/PubMed), Scientific Electronic Library Online (SciELO) and Virtual Health Library (VHL). The query was performed using the controlled descriptors from DeCS/MeSH: "thyroid nodule", "fine needle biopsy", "thyroid", "liquid-based cytology", "molecular test". Moreover, as a result we obtained a general review about the appropriateness of FNAB of the thyroid, an efficient and reliable diagnostic method in the decision and selection of patients who will need surgery. However, this method presents some limitations, such as the need for improvement in the quality of the sample collection or in its interpretation, limitations that can be reduced, decreasing the cases of false positives and negatives, when collected by experienced professionals, guided by ultrasound, and can be combined with color Doppler, as well as, seek opinions from other specialists. The present study also addressed the new diagnostic methods for thyroid nodules, such as liquid-based cytology, used as a technique in conjunction with conventional smears when ancillary techniques are applied, and molecular tests, which have given professionals the opportunity to provide a more accurate evaluation in cases of indeterminate nodules. With this, we reiterate the importance of identifying the best individualized strategy for the patient, preventing unnecessary procedures and offering improved quality of life.
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甲状腺细针穿刺的适宜性评价
本研究旨在对甲状腺FNAB及其在甲状腺结节中的作用进行综合文献综述,FNAB作为早期甲状腺癌的重要诊断工具,在临床上是一种复发性病理。在方法方面,由于这是一篇综合文献综述,因此通过描述性研究,我们使用了医学文献分析与检索系统在线(Medline/PubMed)、科学电子图书馆在线(SciELO)和虚拟健康图书馆(VHL)等数据库。查询使用来自DeCS/MeSH的控制描述符:“甲状腺结节”,“细针活检”,“甲状腺”,“液体细胞学”,“分子测试”。此外,我们对甲状腺FNAB的适用性进行了综述,FNAB是一种有效可靠的诊断方法,可用于决定和选择需要手术的患者。然而,这种方法存在一些局限性,如需要提高样本采集的质量或其解释,限制可以减少,减少假阳性和阴性的情况下,由经验丰富的专业人员收集,在超声指导下,可以结合彩色多普勒,以及征求其他专家的意见。本研究还讨论了甲状腺结节的新诊断方法,如液体细胞学,当辅助技术应用时,作为与传统涂片相结合的技术,以及分子测试,这使专业人员有机会在不确定结节的情况下提供更准确的评估。因此,我们重申为患者确定最佳个性化策略的重要性,防止不必要的手术,提高生活质量。
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