Hypertension in renal transplantation

Abstract

Renal transplantation has become the modality of choice for patients with end stage renal disease. Though it has led to improvement in survival and quality of life mortality still remains high. Cardiovascular disease is the most common cause of mortality in post-renal transplant patients. Hypertension (HTN) being the major traditional risk factor for atherosclerotic cardiovascular disease develops in up to 60–80% of renal allograft recipients. Risk factor for hypertension includes both patient and donor related factor. The major patient related factor includes the use of corticosteroids, calcineurin inhibitors (CNI) and transplant renal artery stenosis (TRAS). In this review we analyze the risk factors, pathogenesis and management of post-renal hypertension.