Biocompatibility and Dissolution Profile of FDM 3D Printed PETG Tablets

P. Arany, Alexa Király, P. Fehér, Z. Ujhelyi, M. Vecsernyés, Marianna Zichar, I. Papp, I. Bácskay
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引用次数: 1

Abstract

Individualized dose is one of the most emerging problems in the pharmaceutical sciences that can be solved with personalized medication. For the manufacturing of personalized medications we can use 3D printing which promise to manufacture complex, personalized products through a low-cost manufacturing process on-demand. 1 3D printing is an umbrella term referring to different techniques but for our experiments we used FDM (fused deposition modeling) technique because it is an off-patent, widespread and inexpensive technology.2 Polyethylene terephthalate glycol (PETG) removes the hazing effect during heating and prevents the undesirable crystallization effect that causes standard PET to become brittle during the FDM printing this is we we choose this polymer for 3D printing. 3
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FDM 3D打印PETG片的生物相容性和溶出度
个体化剂量是医药科学中最新兴的问题之一,可以通过个体化用药来解决。对于个性化药物的制造,我们可以使用3D打印,它有望通过低成本的按需制造过程制造复杂的个性化产品。3D打印是一个总称,指的是不同的技术,但在我们的实验中,我们使用了FDM(熔融沉积建模)技术,因为它是一种非专利、广泛且廉价的技术聚对苯二甲酸乙二醇酯(PETG)消除了加热过程中的雾化效应,并防止了在FDM打印过程中导致标准PET变脆的不良结晶效应,这就是我们选择这种聚合物进行3D打印的原因。3.
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