Anhedonia in Unipolar Major Depressive Disorder: A Review~!2009-10-26~!2010-02-18~!2010-04-08~!

G. Dichter
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引用次数: 58

Abstract

Anhedonia, the decreased capacity to experience pleasure, is a defining symptom of unipolar major depressive disorder (MDD). This review summarizes definitions and measurement issues related to the assessment of hedonic capacity in MDD, epidemiological research addressing linkages between anhedonia and MDD, as well as biomedical research investigating the neurobiology of anhedonia in both pre-clinical and clinical contexts. A synthesis of available data is presented that suggests that anhedonia is a core symptom of MDD, the elucidation of which is critical for improved understanding, detection, and treatment of MDD.
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单极重性抑郁障碍的快感缺乏研究进展2009-10-26 2010-02-18 2010-04-08
快感缺乏,即体验快乐的能力下降,是单极重性抑郁症(MDD)的典型症状。本文综述了与重度抑郁症中享乐能力评估相关的定义和测量问题,研究享乐缺乏和重度抑郁症之间联系的流行病学研究,以及在临床前和临床背景下调查享乐缺乏神经生物学的生物医学研究。综合现有数据提出,快感缺乏是重度抑郁症的核心症状,阐明这一点对于提高对重度抑郁症的理解、检测和治疗至关重要。
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