ASSESSMENT OF THE USE OF DRUG TREATMENT OF DYSLIPIDEMIA AT MILITARY HOSPITAL 105

Tram Vu Thi, Trang Tran Thi Thu, Cong Vu Thanh, Phu Tran Doan, Binh Tran Quoc, Tuan Truong Quoc, L. Nguyen Ngoc
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Abstract

Dyslipidemia characteristics of outpatients with dyslipidemia for the first time, characteristics of drug use, and effectiveness in controlling dyslipidemia indexes after 3 months of treatment at Military Hospital 105 were studied. A crosssectional, retrospective descriptive study was investigated on adult outpatients who were diagnosed with dyslipidemia for the first time, examined and treated as outpatients at the hospital, and monitored for effectiveness in blood lipid control for 3 months after starting treatment. The decision to use the drug at the start of the study and the achievement of treatment goals at the time points were analyzed based on the ESC\EAS 2019 guidelines for treating DL. The majority of patients were aged > 45 years (80.5%), the most common group of patients was aged 46 - 59 (43.7%). The number of patients with comorbidities accounted for 62.8%. 87% of patients had mixed dyslipidemia, 54.8% of patients were in the group with high and very high cardiovascular risk. 93.5% of patients needed to start treatment with drugs based on LDL-C index at the time of treatment initiation. The majority of patients used monotherapy regimens, in which, Statins were used the most in the study sample with the rate of 95.3% in the initial treatment regimen. 70.4% of patients had an inappropriate decision to initiate treatment, of which the most common was the decision to use statins with insufficient dosage in patients (45.1%). Only 28% of patients reached their LDL-C goal after 3 months of treatment. From the high percentage of patients who did not reach the treatment goal in the study sample, it is necessary to consider using stronger statin therapy, higher dose statin, or using another treatment regimen for patients.
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军队医院血脂异常患者用药评价[j]
对105部队医院首次门诊血脂异常患者的血脂异常特点、用药特点及治疗3个月后对血脂异常指标的控制效果进行研究。采用横断面、回顾性描述性研究,对首次诊断为血脂异常的成人门诊患者,在该院作为门诊患者检查治疗,治疗3个月后监测血脂控制效果。根据ESC\EAS 2019治疗DL指南,分析研究开始时使用该药的决定和治疗目标在时间点的实现情况。以年龄> 45岁的患者居多(80.5%),以46 ~ 59岁的患者居多(43.7%)。合并合并症患者占62.8%。87%的患者患有混合性血脂异常,54.8%的患者属于心血管高危和极高危组。93.5%的患者在开始治疗时需要基于LDL-C指数的药物开始治疗。大多数患者使用单一治疗方案,其中他汀类药物在研究样本中使用最多,在初始治疗方案中使用率为95.3%。70.4%的患者有不适当的开始治疗决定,其中最常见的是决定使用他汀类药物剂量不足的患者(45.1%)。治疗3个月后,只有28%的患者达到了LDL-C目标。从研究样本中未达到治疗目标的患者比例较高来看,有必要考虑对患者使用更强的他汀类药物治疗、更高剂量的他汀类药物或使用其他治疗方案。
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