A deep learning method for lincRNA identification using auto-encoder algorithm

Abstract

LincRNAs are four times more than coding RNA sequences. However, currently only 21 thousand lincRNAs are computationally discovered [1]. Although this was one of the most important findings in lincRNA identification, identification of lincRNAs is far from being complete and those predicted lincRNAs are not validated yet. Currently new identified lincRNAs are most from the computational analysis of RNA-seq transcript data while deep learning based methods are barely seen in detecting and validating lincRNAs.