Fibroepithelial Breast Tumors: Cohort Study

Abstract

Background: The frequency of mesenchymal breast tumors is very low, being represented mostly by tumors with biphasic proliferation (phyllodes tumors) and less by other types of non-epithelial tumors. Objective: To review the Management of phyllodes tumors of the breast in the NCI Cairo university during a period of 10 years (2000 till 2010). Material and Methods: Retrospective study including 99 patients who diagnosed and treated with phyllodes tumors of the breast between (2000 to 2010). Data were collected from the biostatistics and cancer epidemiology department. Results: Out of 99 patients; 51 (51.5%) were benign and 32 (32.3%) were borderline and 16 (16%) were malignant; the median age of the study population was 45.5 years (range 18–71 years).The main radiological tool of diagnosis was breast US and mammography 100%. Preoperative fine needle aspiration (FNA) was performed in 12(37.5%) cases for cytodiagnosis but true cut biopsy was done in 87 (87%) cases. Wide local excision was done in 86%, wide local excision with axillary evacuation was done in 1% only, simple mastectomy was done in 9.3% and modified radical mastectomy was done only in 3% of all cases. Conclusion: Different surgical modalities are considered the main line for management of phyllodes breast tumors. Local recurrence can be avoided with wide local excision from the first surgery. Axillary LN dissection is not a role in management of breast PT.