{"title":"짝자래나무 메탄올추출물의 항산화 활성 및 항주름 효과","authors":"Hyun-Ok Kim, 오창종, 장병철, Kim, Young Chul","doi":"10.15810/JIC.2018.14.4.003","DOIUrl":null,"url":null,"abstract":"The objectives of this study were to investigate the antioxidant activity and anti-wrinkle effect of Rhamnus yoshinoi methanol extract (RYME) in a cell-free system. The total polyphenol and flavonoids contents in RYME were 538.4 and 196.3 mg/g, respectively. The electron-donating ability of RYME at 100 μg/mL was 92.5%, while its collagenase and elastase inhibitory effects at 8,000 μg/mL were 53.4 and 41.7%, respectively. In comparison, collagenase and elastase inhibition of the positive control vitamin C were 51.0 and 32.7%, respectively. The present study demonstrated that RYME has high antioxidant activity and effectively inhibited the activities of collagenase and elastase.","PeriodicalId":16256,"journal":{"name":"Journal of Investigative Cosmetology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Investigative Cosmetology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15810/JIC.2018.14.4.003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The objectives of this study were to investigate the antioxidant activity and anti-wrinkle effect of Rhamnus yoshinoi methanol extract (RYME) in a cell-free system. The total polyphenol and flavonoids contents in RYME were 538.4 and 196.3 mg/g, respectively. The electron-donating ability of RYME at 100 μg/mL was 92.5%, while its collagenase and elastase inhibitory effects at 8,000 μg/mL were 53.4 and 41.7%, respectively. In comparison, collagenase and elastase inhibition of the positive control vitamin C were 51.0 and 32.7%, respectively. The present study demonstrated that RYME has high antioxidant activity and effectively inhibited the activities of collagenase and elastase.
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