Inhalation Insufflation Technique with Local Anaesthetic Spray without Intubation and Opioids for Paediatric Upper Airway Surgery - Observational Case Series Study

V. R. Kadam
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Abstract

Anaesthetic management of upper airway surgery in paediatric is challenging. Total intravenous anaesthesia with opioid or inhalation technique with spontaneous respiration has been used but studies are limited on inhalation technique. This study aimed to use tubeless inhalation insufflation technique without opioids at a tertiary centre. All paediatric patients coming for elective upper airway surgery to the centre, were included. Mask induction was with 5-8% sevoflurane in O2 and maintenance with 2-3%, via a nasopharyngeally placed Endotracheal Tube (ETT) or catheter on spontaneous ventilation with flow between 8-10 l/min. Lidocaine up to 5 mg/kg was then sprayed to the mucosa of larynx and trachea. Once adequate depth was attained, suspension laryngoscope was placed by a surgeon for surgery. Some complications were observed i.e inadequate anaesthesia requiring rescue drugs like opioids or propofol, intubation, desaturation events from laryngospasm and delayed recovery. Surgical technique involved was diagnostic and therapeutic for the upper airway lesions. Fifteen paediatric patients (2 months to 7 yrs) were included in the study with tubeless anaesthesia. None of them required intubation during the procedure. The mean time from induction of anaesthesia to unconsciousness was 15 ± 3 s and attainment of necessary anaesthetic depth for surgery was 4.7 ± 0.90 min. None had desaturation events or required opioids. However, propofol was required in one and delayed anaesthetic recovery was observed in one patient. This study on tubeless anaesthesia with Local Anaesthetic (LA) spray with spontaneous inhalation insufflation technique provided an opioid-free, interference-free operative field without airway compromise, not requiring intubation, therefore, further studies are required.
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无插管和阿片类药物的局部麻醉喷雾吸入技术在儿科上呼吸道手术中的应用——观察性病例系列研究
小儿上呼吸道手术麻醉管理具有挑战性。阿片类药物全静脉麻醉或自主呼吸吸入技术已被应用,但对吸入技术的研究有限。本研究的目的是在三级中心使用无阿片类药物的无管吸入注入技术。所有到该中心进行选择性上呼吸道手术的儿童患者均被纳入。面罩诱导用5-8%七氟醚O2,维持用2-3%,通过鼻咽部放置气管内管(ETT)或导管,自动通气,流量8- 10l /min。然后将5 mg/kg的利多卡因喷至喉部和气管粘膜。一旦达到足够的深度,由外科医生放置悬吊喉镜进行手术。观察到一些并发症,如麻醉不充分,需要阿片类药物或异丙酚等抢救药物,插管,喉痉挛引起的去饱和事件和恢复延迟。所涉及的手术技术是诊断和治疗上气道病变。15名儿童患者(2个月至7岁)被纳入无管麻醉研究。在手术过程中,他们都不需要插管。从麻醉诱导到昏迷的平均时间为15±3 s,达到手术所需麻醉深度为4.7±0.90 min。没有发生去饱和事件或需要阿片类药物。然而,1例患者需要异丙酚,1例患者观察到延迟麻醉恢复。本研究采用局部麻醉(Local Anaesthetic, LA)喷雾剂与自主吸入灌注技术的无管麻醉提供了无阿片类药物、无干扰、不损害气道、不需要插管的手术野,因此,需要进一步的研究。
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