Obesity and COVID-19 Outcomes in a Primarily Black Population

Raj K. Dangol, O. Lurye, Sadaf Mustafa, L. Camire, Krupa Patel, E. Tefera, David S. Weisman
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Abstract

Abstract ABSTRACT Background: Studies have noted higher COVID-19 mortality with more severe obesity in populations that included a small percentage of Black patients. Methods: We retrospectively analyzed COVID-19 outcomes associated with obesity in our largely African American patient population. A total of 1101 symptomatic patients with a positive COVID-19 laboratory test March 5 to June 3, 2020, were categorized into weight groups based on body mass index (BMI). Of these patients, 679 (61.7%) were Black. A total of 355 (32.2%) patients had overweight and 516 (46.9%) had obesity. Results: BMI was an independent risk factor for intubation and an independent predictor for ICU length of stay and intubation days. An unexpected observation was favorable outcomes in mild obesity compared with normal weight and more severe obesity, likely a result of older age and higher Charlson comorbidity index in patients with normal BMI compared with patients with mild obesity. Conclusions: Abstract Background : Studies have noted higher COVID-19 mortality with more severe obesity in populations that included a small percentage of Black patients. Methods : We retrospectively analyzed COVID-19 outcomes associated with obesity in our largely African American patient population. A total of 1101 symptomatic patients with a positive COVID-19 laboratory test March 5 to June 3, 2020, were categorized into weight groups based on body mass index (BMI). Of these patients, 679 (61.7%) were Black. A total of 355 (32.2%) patients had overweight and 516 (46.9%) had obesity. Results : BMI was an independent risk factor for intubation and an independent predictor for ICU length of stay and intubation days. An unexpected observation was favorable outcomes in mild obesity compared with normal weight and more severe obesity, likely a result of older age and higher Charlson comorbidity index in patients with normal BMI compared with patients with mild obesity. Conclusions : In a diverse primarily Black population, comorbidities were a concern for adverse COVID-19 outcomes and COVID-19 outcomes were signi fi cantly worse with moderate and severe obesity.
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主要黑人人群的肥胖和COVID-19结局
背景:研究表明,在包括一小部分黑人患者在内的人群中,COVID-19死亡率更高,肥胖程度更严重。方法:我们回顾性分析了以非裔美国人为主的患者人群中与肥胖相关的COVID-19结局。根据身体质量指数(BMI)将2020年3月5日至6月3日新冠肺炎实验室检测呈阳性的症状患者1101例分为体重组。其中679例(61.7%)为黑人。超重355例(32.2%),肥胖516例(46.9%)。结果:BMI是插管的独立危险因素,也是ICU住院时间和插管天数的独立预测因子。一个意想不到的观察结果是,与正常体重和更严重的肥胖患者相比,轻度肥胖患者的预后较好,这可能是由于BMI正常的患者年龄较大,且与轻度肥胖患者相比,其Charlson合病指数较高。背景:研究表明,在包括一小部分黑人患者在内的人群中,COVID-19死亡率更高,肥胖程度更严重。方法:我们回顾性分析了以非裔美国人为主的患者人群中与肥胖相关的COVID-19结局。根据身体质量指数(BMI)将2020年3月5日至6月3日新冠肺炎实验室检测呈阳性的症状患者1101例分为体重组。其中679例(61.7%)为黑人。超重355例(32.2%),肥胖516例(46.9%)。结果:BMI是插管的独立危险因素,也是ICU住院时间和插管天数的独立预测因子。一个意想不到的观察结果是,与正常体重和更严重的肥胖患者相比,轻度肥胖患者的预后较好,这可能是由于BMI正常的患者年龄较大,且与轻度肥胖患者相比,其Charlson合病指数较高。结论:在以黑人为主的多样化人群中,合并症是COVID-19不良结局的一个关注点,中度和重度肥胖患者的COVID-19结局明显更差。
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