Idiopathic Granulomatous Mastitis: In Search of a Therapeutic Template

S. Khan, A. Ali
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Abstract

Background: Granulomatous mastitis also known as granulomatous inflammatory lesionsof the breast can be divided into idiopathic granulomatous mastitis and granulomatousmastitis occurring as a rare secondary complication of a great variety of other conditions.Treatment is radically different for idiopathic granulomatous mastitis and other granulomatouslesions of the breast, the precise diagnosis is therefore very important. Objectives: The purpose of this study was to find the clinicopathological features ofidiopathic granulomatous mastitis, as well as the authors' experience with surgicaltreatment of these patients. Methods and Materials: A hospital based retrospective study done with twenty diagnosedpatients of idiopathic granulomatous mastitis enrolled from department of surgery, Ad-dinwomen's.medical college hospital, Dhaka in the period between July 2012- July 2015. Results: Mean age of presentation was 38.1 years. All patients had a history of childbirthand breastfeeding. Sixteen (80%) patients were premenopausal. The main clinical featurewas a mass in the breast in all patients and clinical findings suggesting an infection accompaniedthe mass in seven patients (35%). Surgery was the definitive procedure in allpatients. Wide local excision done in all patients. None of the patients received steroids.Median follow-up time was 12 months. During follow-up, two patients (10%) presented withrecurrence. All patients with recurrence had a mass in their breasts on the same side ofprevious disease. Conclusion: Increased recognition of this disease will improve its understanding andmanagement. Long-term follow-up is necessary. Journal of Surgical Sciences (2016) Vol. 20 (2) :51-54
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特发性肉芽肿性乳腺炎:寻找治疗模板
背景:乳腺肉芽肿性乳房炎也称为肉芽肿性炎性病变,可分为特发性肉芽肿性乳房炎和肉芽肿性乳房炎,是一种罕见的继发性并发症,发生于多种其他疾病。特发性肉芽肿性乳腺炎与乳腺其他肉芽肿性病变的治疗方法截然不同,因此准确的诊断非常重要。目的:本研究的目的是发现原发性肉芽肿性乳腺炎的临床病理特征,以及作者对这些患者的手术治疗经验。方法和材料:对20例诊断为特发性肉芽肿性乳腺炎的患者进行回顾性研究。2012年7月至2015年7月期间,达卡医学院医院。结果:平均发病年龄为38.1岁。所有患者均有分娩和母乳喂养史。16例(80%)患者处于绝经前。所有患者的主要临床特征为乳房肿块,7例(35%)患者临床表现提示肿块伴感染。手术是所有患者的最终治疗方法。所有患者均行大面积局部切除。所有患者均未接受类固醇治疗。中位随访时间为12个月。随访期间,2例(10%)出现复发。所有复发的患者在既往疾病的同侧乳房上都有肿块。结论:提高对本病的认识有助于提高对本病的认识和治疗。长期随访是必要的。外科杂志(2016)Vol. 20 (2):51-54
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