A study on prescribing pattern and medication adherence in elderly COPD and bronchial asthma patients in a tertiary care teaching hospital

Anbu D., Benimana Grace, M. K., B. K.
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Abstract

Background: Chronic obstructive pulmonary disease and bronchial asthma are common among elderly people and have become a major public health concern of today. The purpose of this study is to identify the prescription pattern and role of medication adherence in the COPD and bronchial asthma. Prescription pattern monitoring (PPMS) are mainly focus on prescribing, dispensing, administering of drugs they promote appropriate use of monitored drugs and reduction of abuse/misuse.Methods: A hospital based prospective observational study was conducted at department of medicine in Rajah Muthiah Medical College and Hospital. A total of 90 patients were enrolled based on inclusion and exclusion criteria and the data was collected using designed data collection form.Results: Out of 90 patients, male (81.10%) and female (18.90%) are reported with COPD and bronchial asthma. On prevalence 57 (63.34%) of patients with co-morbidities and without co-morbidities 33 (36.66%). Among co-morbidity patients, 38.90% of patients has type-2 diabetes mellitus. PPA indicate that cephalosporins (46.68%), macrolides (38.88%) class of antibiotic are used prominently along with corticosteroids of hydrocortisone 47 (62.66%) and prednisolone 28 (37.34%). 47 (62.66%) patients received expectorants and anti-tussive in that, Ipratropium bromide + levosalbutamol (50%) are commonly prescribed.Conclusions: This study concludes that COPD and bronchial asthma was most predominant in elderly patients and its treated with mainly antibiotics and corticosteroids with bronchodilators in the way of inhalers and nebulizers. The rational use of drugs and patient counselling reflects a better medication adherence.
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某三级教学医院老年COPD及支气管哮喘患者的处方模式及依从性研究
背景:慢性阻塞性肺疾病和支气管哮喘在老年人中很常见,已成为当今主要的公共卫生问题。本研究的目的是确定处方模式和药物依从性在慢性阻塞性肺病和支气管哮喘中的作用。处方模式监测(PPMS)主要侧重于药物的处方、调剂和给药,促进监测药物的适当使用和减少滥用/误用。方法:在Rajah Muthiah医学院和医院内科进行了一项以医院为基础的前瞻性观察研究。根据纳入和排除标准共入组90例患者,采用设计的数据收集表收集数据。结果:90例患者中,男性(81.10%)和女性(18.90%)合并COPD和支气管哮喘。有合并症57例(63.34%),无合并症33例(36.66%)。在合并症患者中,38.90%的患者有2型糖尿病。PPA显示头孢菌素类抗生素(46.68%)、大环内酯类抗生素(38.88%)、氢化可的松47类(62.66%)和泼尼松龙28类(37.34%)的使用最为普遍。47例(62.66%)患者使用祛痰和止咳药,其中常用异丙托溴铵+左沙丁胺醇(50%)。结论:COPD合并支气管哮喘以老年患者为主,治疗以抗生素和皮质类固醇为主,支气管扩张剂以吸入器和雾化器为主。合理用药和患者咨询反映了更好的药物依从性。
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