{"title":"microRNA-181b通过靶定 MLK2 调节白血病细胞HL-60的增殖","authors":"米延 陈宏陈群方明, Chen Qun Fang Meng Mi Yan Chen Hong","doi":"10.1360/ZC2009-39-11-1034","DOIUrl":null,"url":null,"abstract":"microRNA在细胞的转移、凋亡、分化等生命过程中发挥着重要的作用. miR-181b在急髓性白血病组织中高表达, 通过靶定MLK2调节急髓性白血病细胞的增殖. 本结果提示, miR-181b在急髓性白血病的生物学过程发挥着重要的作用, 同时为急髓性白血病的治疗提供了新的解决方案.","PeriodicalId":49127,"journal":{"name":"Science in China. Series C, Life Sciences / Chinese Academy of Sciences","volume":"18 1","pages":"1034-1040"},"PeriodicalIF":0.0000,"publicationDate":"2009-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science in China. Series C, Life Sciences / Chinese Academy of Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1360/ZC2009-39-11-1034","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}