Surgical Outcome of Spinal Tuberculosis Regarding Pain, Neurological Deficit, and Spinal Instability

Ehtisham Ahmed khan Afridi, Ahsan Aurangzeb Khan, Saadia Maqbool, Nusrat Shaheen
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Abstract

Objective:  The most prevalent type of skeletal TB, which accounts for nearly half of all cases, affects the spinal column. Regarding pain, neurological deficit, and spinal instability, the study sought to determine the surgical outcome of spinal tuberculosis. Material and Methods:  This study was conducted in the Department of Neurosurgery, Ayub Teaching Hospital. A total of 42 patients with ages ranging from 24 – 66 years were included in the study. Information about the patient was gathered to determine indications (neurological impairments) about the ASIA Grading Scale and frequently affected areas. Results:  Commonest location was a thoracolumbar junction in 42.8%, followed by the lumbar spine in 23.8%. The pain was found in all subjects. The main indication of surgery was neurological deficit which is seen in 57% of patients followed by spinal instability or deformity in 16.6% of patients and patients with failed chemotherapy in 4.7% of patients. The preoperative KA was between 30 – 60º with a mean of 43.06 ± 4.11 degrees and 9.45 ± 3.99 degrees for postoperative KA (p-value < 0.0001). Most fixations of the cord were done through a posterior approach that was in 83.3% of patients. The neurological improvement according to ASIA grading was seen in 95.2% and no improvement was seen in 4.7% of patients upon 3 months follow-up. Conclusion:  Surgical treatment of the caries spine improves pain, lowers neurological compression, and successfully reverses deformities like kyphosis, resulting in better clinical results. It also helps to remove the Tuberculous burden from the body.
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脊柱结核的手术结果与疼痛、神经功能缺损和脊柱不稳定有关
目的:最常见的骨骼结核类型,占所有病例的近一半,影响脊柱。关于疼痛、神经功能缺损和脊柱不稳定,该研究试图确定脊柱结核的手术结果。材料与方法:本研究在Ayub教学医院神经外科进行。研究共纳入42例患者,年龄在24 - 66岁之间。收集有关患者的信息,以确定有关ASIA分级量表的指征(神经损伤)和经常受影响的区域。结果:最常见的部位是胸腰椎交界处(42.8%),其次是腰椎(23.8%)。所有受试者都感到疼痛。手术的主要指征是57%的患者出现神经功能缺损,其次是16.6%的患者出现脊柱不稳定或畸形,4.7%的患者化疗失败。术前KA在30 ~ 60º之间,平均43.06±4.11度,术后平均9.45±3.99度(p值< 0.0001)。大多数脊髓固定是通过后路完成的,占83.3%的患者。在3个月的随访中,95.2%的患者的神经系统得到改善,4.7%的患者没有得到改善。结论:手术治疗脊柱龋病可改善疼痛,减轻神经压迫,成功逆转脊柱后凸等畸形,临床效果较好。它还有助于消除体内的结核负担。
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