{"title":"Regression of Diabetic Macular Edema by Remission of Type 2 Diabetes with Plant-Based Diet: A Case Report and Review","authors":"Panigrahi Gunadhar","doi":"10.23937/2378-3656/1410381","DOIUrl":null,"url":null,"abstract":"The current practice in the management DR has been primarily aimed at its neovascular complications, and rests upon the use of laser photocoagulation, intravitreal anti-VGEF injections, and on occasion glucocorticoid therapy. However, these treatments are not curative and there is increasing evidence that anti-VEGF treatment is unlikely to improve retinal perfusion and may not prevent gradual progression of nonperfusion or loss of peripheral visual field associated with worsening diabetes-related eye disease [7]. Moreover, there are many short term and long-term complications associated with these treatments. Diabetic retinopathy is the result of the convergence of many metabolic abnormalities leading to retinal vasculature dysfunction, inflammation, and neurodegeneration [8]. DR has been considered a microcirculatory disease of the retina. However, there is emerging evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of DR [9]. Introduction","PeriodicalId":10450,"journal":{"name":"Clinical Medical Reviews and Case Reports","volume":"221 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medical Reviews and Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2378-3656/1410381","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
The current practice in the management DR has been primarily aimed at its neovascular complications, and rests upon the use of laser photocoagulation, intravitreal anti-VGEF injections, and on occasion glucocorticoid therapy. However, these treatments are not curative and there is increasing evidence that anti-VEGF treatment is unlikely to improve retinal perfusion and may not prevent gradual progression of nonperfusion or loss of peripheral visual field associated with worsening diabetes-related eye disease [7]. Moreover, there are many short term and long-term complications associated with these treatments. Diabetic retinopathy is the result of the convergence of many metabolic abnormalities leading to retinal vasculature dysfunction, inflammation, and neurodegeneration [8]. DR has been considered a microcirculatory disease of the retina. However, there is emerging evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of DR [9]. Introduction