Caroline A Cobine, Karen I. Hannigan, Megan McMahon, Emer Ni Bhraonain, S. Baker, K. Keef
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引用次数: 5
Abstract
The internal anal sphincter (IAS) exhibits slow waves (SWs) and tone that are dependent upon L‐type Ca2+ channels (CavL) suggesting that phasic events (ie, SWs) play a fundamental role in tone generation. The present study further examined phasic activity in the IAS by measuring the spatiotemporal properties of Ca2+ transients (CTs) in IAS smooth muscle cells (SMCs).