Calcium and vitamin D supplementation to pregnant women in urban hospital and community settings

A. Pramanik, Ravindranadh Palika, R. Pullakhandam, K. Kalaivani, P. Ramachandran
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Abstract

In India, calcium intake is low and the prevalence of Vitamin D deficiency in pregnant women is high. The National Guidelines envisage elemental calcium 500 mg (as calcium carbonate salt) and 250 IU vitamin D supplements should be provided to pregnant and lactating women. In Delhi, iron folic acid tablets are given twice a day after meals in anaemic women and one tablet of calcium and vitamin D daily after a meal in all pregnant women. A study was taken up to assess the availability and compliance with calcium and vitamin D supplementation in primary health care institutions under research (Group 1 - 387 women) and service conditions (Group 2 - 400 women) and in urban community setting (Group 3 - 448 women). Women in Group 1 received Ca and Vitamin D tablets regularly from the research staff. In Group 2 and Group 3 tablets, were provided as and when government supplies were available and prescriptions were given when they were not available. Ca and Vitamin D tablets were expensive; families bought the tablets as and when they had the funds. As a result, the number of tablets available for consumption was lower in Group 2 and 3. In all three groups, side effects were rare and nearly all available tablets were consumed. In Group 1, Vitamin D estimation was done at enrolment and after supplementation for three months; 83% of women at enrolment and 68% of women after three months of supplementation had serum vitamin D levels below 20 ng/ml. These data suggest that one tablet of Ca and Vit D per day is insufficient for correcting maternal vitamin D deficiency. It is essential to carry out studies to assess the impact of supplementation with two tablets of Ca and Vit D on maternal vitamin D levels.
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向城市医院和社区孕妇补充钙和维生素D
在印度,孕妇的钙摄入量很低,维生素D缺乏症的发生率很高。国家指南设想应向孕妇和哺乳期妇女提供500毫克元素钙(作为碳酸钙盐)和250国际单位维生素D补充剂。在德里,贫血妇女每天饭后服用两次叶酸铁片,所有孕妇每天饭后服用一片钙和维生素D片。进行了一项研究,以评估初级保健机构(第1组- 387名妇女)和服务条件(第2组- 400名妇女)以及城市社区环境(第3组- 448名妇女)补充钙和维生素D的情况和遵守情况。第一组的妇女定期从研究人员那里获得钙和维生素D片。在第2组和第3组中,当有政府供应时提供药片,当没有政府供应时提供处方。钙和维生素D片很贵;这些家庭一有了资金就购买了这些平板电脑。结果,第二组和第三组可供消费的片剂数量较少。在所有三组中,副作用很少,几乎所有可用的药片都被消耗掉了。在第1组,在入组时和补充后三个月进行维生素D估算;83%的妇女在入组时和68%的妇女在补充三个月后血清维生素D水平低于20 ng/ml。这些数据表明,每天一片钙和维生素D不足以纠正母亲维生素D缺乏症。有必要开展研究,评估补充两片钙和维生素D对母体维生素D水平的影响。
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