Economic burden of malaria in Burundian children: An evidence for disease management in resource limited settings

Nina Hezagira, S. Youngkong, A. Riewpaiboon
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Abstract

In Burundi, malaria is the leading cause of morbidity and mortality, especially in children under five. This results in high clinical burden of the disease; however, its economic burden remains unknown. The aim of this study was to estimate the economic burden associated with malaria in Burundi and explore the factors that can affect the costs. This study was a prospective incidence-based cost-of-illness study analysed from the societal perspective. The study included children aged under five years with malaria infection, who visited and received treatment at any of the two study health facilities in the period of November to December 2019. Data collection was done by reviewing medical and financial records and by interviewing caregivers of the patients. Micro-costing approach was used to estimate the economic costs of malaria per episode. The cost was presented in international dollars (Int$) for the year 2019. Stepwise multiple linear regression method was applied to examine the factors affecting the costs and to generate a cost model. Eighty-five children with the average age of 29 months were included in the study. Most of them (70.5%) were treated as in-patient. The out-patient visits costed Int$23.5, while the in-patient hospitalization costed Int$218.2. The types of medical services, health facilities, antimalarials used, and duration of fever before seeking appropriate medical care were found to affect the costs. The model indicates that up to Int$18.76 can be saved per malaria episode if treated early (in less than 2 days). This can save up to Int$24,257,748 per year at national level. This study demonstrated that malaria is associated with a considerable economic burden in Burundi. It will support decision makers in deciding an appropriate clinical management for malaria prevention like the community case management program.
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布隆迪儿童疟疾的经济负担:资源有限环境下疾病管理的证据
在布隆迪,疟疾是发病和死亡的主要原因,特别是在五岁以下儿童中。这导致该病的高临床负担;然而,其经济负担仍不得而知。这项研究的目的是估计布隆迪与疟疾有关的经济负担,并探讨可能影响成本的因素。本研究是一项基于发病率的前瞻性疾病成本研究,从社会角度进行分析。该研究包括五岁以下感染疟疾的儿童,他们在2019年11月至12月期间前往两家研究卫生机构中的任何一家接受治疗。数据收集是通过审查医疗和财务记录以及采访患者的护理人员来完成的。采用微观成本计算方法估计疟疾每次发作的经济成本。该费用以2019年的国际美元(Int$)表示。采用逐步多元线性回归方法考察影响成本的因素,并建立成本模型。85名平均年龄为29个月的儿童参与了这项研究。其中以住院为主(70.5%)。门诊诊疗费为23.5新元,住院诊疗费为218.2新元。研究发现,医疗服务的类型、卫生设施、使用的抗疟疾药物以及在寻求适当医疗之前的发烧持续时间会影响到费用。该模型表明,如果及早治疗(不到2天),每次疟疾发作可节省高达18.76美元的费用。这可以在国家一级每年节省高达24,257,748 Int$。这项研究表明,在布隆迪,疟疾与相当大的经济负担有关。它将支持决策者决定适当的疟疾预防临床管理,如社区病例管理方案。
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