Psychosis in Huntington´s Disease. a rare and Under-Investigated Psychiatric Manifestation

M. Gonçalves, C. Ferreira, R. Saraiva, C. Sereijo, L. Castanheira, E. Fernandes, Rita Amaro, T. Mendes, L. Guedes, M. Abreu, I. Chendo
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Abstract

Introduction : Psychotic symptoms are among the least prevalent and under-investigated psychiatric manifestations (PM) of Huntington's disease (HD). Case report : We herein report a case of a 31-year-old male patient who presented PM with a predominance of negative symptoms, without any significant abnormal movement. HD was diagnosed based on positive DNA analysis and family history. HD imposes longitudinal follow-up through a multidisciplinary approach in order to improve the quality of life and prognosis. Conclusion : This case report highlights the importance of comprehending the PM in the initial presentation of HD so that the diagnosis is not delayed until the onset of motor symptoms.
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亨廷顿氏病的精神病。一种罕见且未充分研究的精神病学表现
简介:精神病症状是亨廷顿舞蹈病(HD)最不普遍和研究不足的精神表现(PM)之一。病例报告:我们在此报告一例31岁男性患者,其PM以阴性症状为主,无明显异常运动。根据阳性DNA分析和家族史诊断为HD。HD通过多学科方法进行纵向随访,以改善生活质量和预后。结论:本病例报告强调了在HD的初始表现中理解PM的重要性,这样诊断才不会延迟到运动症状的出现。
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