E EFEKTIVITAS ANALGETIK EKSTRAK BATANG PEPAYA (Carica papaya L.)PADA MENCIT JANTAN YANG DIINDUKSI LEMPENG PANAS

S. Rahmi
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Abstract

Papaya stems (Carica papaya L.) are experimentally utilized by the community as new vegetables. Dried papaya stems contain auxiliary metabolites of flavonoids, tannins, glycosides, polyphenols, steroids and triterpenoids. This compound acts as an antioxidant. The flavonoid compounds found in papaya stems act as analgesics. The point of this ponder was to look at the pain relieving impact of papaya stems on male rats initiated by warm plate. Making wounds on creatures by implies of warming plates made with a estimate of 1cm x 1cm. The hair on the mice's backs was shaved, a warming cushion was connected to the mice's backs for around 2 seconds until they come to the dermis and fundamental tissue, causing the skin to rankle and peel in a few places. Pain relieving perceptions in test creatures were given after acceptance by regulating CMC-Na, paracetamol, papaya stem ethanol extricate at measurements of 100 mg/kgBW, 300 mg/kgBW and 600 mg/kgBW. Papaya stem extricate contains auxiliary metabolites of flavonoids, tannins and saponins that act as analgesics. At a measurements of 600 mg/kg body weight, the extricate had an pain relieving impact comparable to that of paracetamol.
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木瓜茎提取物(Carica papaya L)的镇痛作用。在雄性订做热板时
番木瓜茎(Carica Papaya L.)作为一种新型蔬菜被实验利用。番木瓜干茎含有黄酮类、单宁类、糖苷类、多酚类、类固醇类和三萜类的辅助代谢物。这种化合物起抗氧化剂的作用。木瓜茎中发现的类黄酮化合物具有镇痛作用。这个思考的重点是看看木瓜茎对雄性大鼠的疼痛缓解作用。用热板在动物身上制造伤口,热板的尺寸估计为1cm × 1cm。老鼠背上的毛被剃光,一个温暖的垫子被连接在老鼠背上大约2秒钟,直到它们到达真皮层和基本组织,导致皮肤在一些地方产生刺痛和剥落。通过调节CMC-Na、扑热息痛、番木瓜茎乙醇提取物(分别为100 mg/kgBW、300 mg/kgBW和600 mg/kgBW),给试动物接受后的镇痛感觉。木瓜茎提取物含有辅助代谢物类黄酮,单宁和皂苷,作为镇痛药。在测量600毫克/公斤体重时,提取物具有与扑热息痛相当的疼痛缓解作用。
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