Leila H. Sayed, Hossam Mohamed, Sary Khaleel Abd Elghaffar, Gamal Badr
{"title":"Therapeutic potential of Bee gomogenat against testicular damage in a streptozotocin- induced type I diabetic mouse model","authors":"Leila H. Sayed, Hossam Mohamed, Sary Khaleel Abd Elghaffar, Gamal Badr","doi":"10.21608/aunj.2022.134540.1008","DOIUrl":null,"url":null,"abstract":"Diabetes Mellitus (DM) is a metabolic disorder that has serious effects for male fertility. Additionally, DM mediates impairment of spermatogenesis; decrease in sperm count, viability, and motility; and apoptosis in both somatic and germ cells. This study aimed to investigate the dietary effect of bee gomogenat (BG) supplementation on the architecture of testis in a mouse model of streptozotocin (STZ)-induced type 1 diabetes (TID). Mice were allocated to three different groups: control non-diabetic, YAP+ Leydig cells and the testosterone level. Furthermore, Treatment of diabetic","PeriodicalId":8568,"journal":{"name":"Assiut University Journal of Multidisciplinary Scientific Research","volume":"145 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Assiut University Journal of Multidisciplinary Scientific Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/aunj.2022.134540.1008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Diabetes Mellitus (DM) is a metabolic disorder that has serious effects for male fertility. Additionally, DM mediates impairment of spermatogenesis; decrease in sperm count, viability, and motility; and apoptosis in both somatic and germ cells. This study aimed to investigate the dietary effect of bee gomogenat (BG) supplementation on the architecture of testis in a mouse model of streptozotocin (STZ)-induced type 1 diabetes (TID). Mice were allocated to three different groups: control non-diabetic, YAP+ Leydig cells and the testosterone level. Furthermore, Treatment of diabetic
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