The most common route of administration used during COVID-19

Mena Raid Khalil, Ghaidaa S. Hameed, Dalya Basil Hanna
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Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the virus that caused the COVID-19 pandemic. Initial symptoms include fever, cough, and dyspnea. Symptoms include nausea, vomiting, and abdominal pain, GIT involvement is also possible. The COVID-19 outbreak has increased the need for alternative medicine administration routes, particularly in public places. Buccal, sublingual, and rectal administration are all considered transmucosal methods. They are self-administration options for non-invasive systemic distribution. In addition, they are great for use in palliative and end-of-life care because of their quick onset of action and decreased first-pass metabolism. A mucosal atomization device allows for the intranasal administration of a parenteral formulation through nasal spray. Rectal mucosal absorption is comparable to that of the oral route, making the rectal route an extremely versatile and useful method of drug administration for a wide variety of medications. Covid-19 illness is treated with a variety of drugs, including anti-malaria medication (hydroxychloroquine), glucocorticoids (dexamethasone), antibiotics (azithromycin), and antiviral medications (favipiravir). This article discusses the route of drug administration for COVID-19, as well as symptoms, treatments, and the various ways it can be spread
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COVID-19期间最常用的给药途径
严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)是导致COVID-19大流行的病毒。最初的症状包括发烧、咳嗽和呼吸困难。症状包括恶心、呕吐和腹痛,也可能累及GIT。COVID-19疫情增加了对替代药物给药途径的需求,特别是在公共场所。口腔、舌下和直肠给药都被认为是经粘膜方法。它们是非侵入性全身分布的自我给药选择。此外,他们是伟大的用于姑息治疗和临终关怀,因为他们的快速开始的行动和减少首过代谢。一种粘膜雾化装置,允许通过鼻喷雾剂在鼻内给药。直肠粘膜吸收与口服途径相当,使直肠途径成为一种非常通用和有用的药物给药方法,适用于各种药物。Covid-19疾病可以用多种药物治疗,包括抗疟疾药物(羟氯喹)、糖皮质激素(地塞米松)、抗生素(阿奇霉素)和抗病毒药物(法匹拉韦)。本文讨论了COVID-19的药物给药途径,以及症状、治疗方法和各种传播途径
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