Miscarriage in a patient with Glanzmann Thrombasthenia and low ovarian reserve: A case report

Abstract

Glanzmann thrombasthenia (GT), which has an autosomal inheritance pattern, is a hemorrhagic disorder mostly complicated by mucocutaneous bleeding. The severity of this bleeding disorder varies from mild bruising to frequent severe bleeding. Prepartum, peripartum and postpartum bleeding risks are increased in these patients. In addition to the hemorrhagic complications that endanger maternal and fetal well-being, the risk of miscarriage is increased due to maternal antibodies to the platelets found on conceptus-derived trophoblast (placental) cells. In this case report, we report a patient who had a miscarriage in 7+1 week. Our patient had GT, low ovarian reserve, HPV positivity, bilateral dermoid cyst and was complicated by infertility.