M. Fränzl, T. Thalheim, J. Adler, D. Huster, F. Cichos
{"title":"Single Amyloid Fibrils Studied in a Thermophoretic Trap","authors":"M. Fränzl, T. Thalheim, J. Adler, D. Huster, F. Cichos","doi":"10.1364/oma.2019.am2e.3","DOIUrl":null,"url":null,"abstract":"The aggregation of proteins into amyloid fibrils is fundamental for the understanding of neurodegenerative disorders. Here, we demonstrate a method for the investigation of growth and breakup of single Aβ40 amyloid fibrils in a thermophoretic trap.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"102 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/oma.2019.am2e.3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The aggregation of proteins into amyloid fibrils is fundamental for the understanding of neurodegenerative disorders. Here, we demonstrate a method for the investigation of growth and breakup of single Aβ40 amyloid fibrils in a thermophoretic trap.