Physical Activity and Nutrition INfluences in Ageing: Current Findings from the PANINI Project

A. Whittaker, E. Asamane, J. Aunger, D. Bondarev, A. Cabbia, P. Doody, N. Gensous, Barbara Iadarola, K. Ramsey, Belina Rodrigues, Muhammad Rizwan Tahir, S. Yeung
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引用次数: 8

Abstract

Background: The ageing of the population is a global challenge and the period of life spent in good health, although increasing, is not keeping pace with lifespan. Consequently, understanding the important factors that contribute to healthy ageing and validating interventions and influencing policy to promote healthy ageing are vital research priorities. Method: The PANINI project is a collaboration of 20 partners across Europe examining the influence of physical activity and nutrition in ageing. Methods utilised encompass the biological to the social, from genetics to the influence of social context. For example, epigenetic, immunological, and psychological assessments, and nutritional and sports science-based interventions have been used among older adults, as well as mathematical modelling and epidemiology. The projects are multi-disciplinary and examine health outcomes in ageing from a range of perspectives. Results: The results discussed here are those emerging thus far in PANINI from 11 distinct programmes of research within PANINI as well as projects cross-cutting the network. New approaches, and the latest results are discussed. Conclusions: The PANINI project has been addressing the impact of physical activity and nutrition on healthy ageing from diverse but interlinked perspectives. It emphasises the importance of using standardized measures and the advantages of combining data to compare biomarkers and interventions across different settings and typologies of older adults. As the projects conclude, the current results and final data will form part of a shared dataset, which will be made open access for other researchers into ageing processes.
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身体活动和营养对衰老的影响:来自PANINI项目的最新发现
背景:人口老龄化是一项全球性挑战,健康寿命虽然在增加,但跟不上寿命的增长。因此,了解有助于健康老龄化的重要因素,验证干预措施并影响促进健康老龄化的政策是至关重要的研究重点。方法:PANINI项目是欧洲20个合作伙伴的合作项目,旨在研究身体活动和营养对衰老的影响。所使用的方法包括从生物学到社会,从遗传学到社会背景的影响。例如,在老年人中使用了表观遗传学、免疫学和心理学评估,以及基于营养和运动科学的干预措施,以及数学建模和流行病学。这些项目是多学科的,从一系列角度研究老龄化的健康结果。结果:这里讨论的结果是迄今为止在PANINI中从11个不同的研究项目以及跨网络的项目中出现的结果。讨论了新方法和最新成果。结论:PANINI项目一直在从不同但相互关联的角度研究身体活动和营养对健康老龄化的影响。它强调了使用标准化措施的重要性,以及结合数据比较不同环境和老年人类型的生物标志物和干预措施的优势。随着项目的结束,目前的结果和最终数据将形成一个共享数据集的一部分,该数据集将向其他研究衰老过程的研究人员开放。
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