{"title":"Gene Delivery System: Non-Viral Mediated Chemical Approaches","authors":"N. Khan","doi":"10.4172/2157-7552.1000205","DOIUrl":null,"url":null,"abstract":"Employing cationic lipids and polymers, inorganic nanoparticles, etc. as DNA carriers for gene delivery systems are gaining interest with the passage of time such chemical vectors form condensed complexes or aggregates with negatively charged DNA to not only protect the DNA from nucleases but also facilitate its intracellular uptake and site specific delivery.","PeriodicalId":17539,"journal":{"name":"Journal of Tissue Science and Engineering","volume":"26 1","pages":"1-4"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Tissue Science and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2157-7552.1000205","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Employing cationic lipids and polymers, inorganic nanoparticles, etc. as DNA carriers for gene delivery systems are gaining interest with the passage of time such chemical vectors form condensed complexes or aggregates with negatively charged DNA to not only protect the DNA from nucleases but also facilitate its intracellular uptake and site specific delivery.
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