Drug Safety of Consumers Taking Alcohol Tonic Solutions

C. Yang, C. Hsieh, Weng‐Foung Huang
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Abstract

Alcohol Tonic Solutions (ATS) is one kind of drugs which main components include amino acids and B-complex vitamins, and contain 8% alcohol by volume. The usage direction is to take 30 mL to 40 mL threes times a day as 'nutrition supplement.' However, misunderstandings have caused the misuse of ATS such as to freshen up but overlook the potential risk of overuse. This study focused on the volume of ATS intake, to certain the security when people use it. We recruited 16 male and 16 female volunteer subjects. Their breath alcohol concentration (BrAC) was examined by Roadside Breath Tester IV. Each subject had ATS test under 12 conditions: before or after meal, subjects would take ATS 40 mL, 80 mL, and 120 mL with physical exercise 15 minutes or not. The results showed after meal BrAC was lower than before meal BrAC. BrAC was lower in subjects doing physical exercise after drinking ATS than those without physical exercise. Using multiple regression analysis (R^2=0.56), the BrAC significantly decreased in subjects with higher weight, higher frequency of drinking, meal taken, and physical exercise. Our finding shows the volume-dependent relationship between BrAC and volume of ATS. Also, taking ATS after meal with physical exercise related to lower BrAC.
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消费者服用酒精滋补液的药物安全
酒精补液(ATS)是一类以氨基酸和复合维生素b为主要成分,酒精含量为8%(按体积计)的药物。使用方法为每日三次,每次30毫升至40毫升,作为“营养补充”。然而,一些误解导致了ATS的误用,比如为了洗漱而忽视了潜在的过度使用风险。本研究的重点是ATS的摄入量,以确定人们使用时的安全性。我们招募了16名男性和16名女性志愿者。通过路边呼吸测试仪IV检测受试者的呼气酒精浓度(BrAC)。受试者在餐前或餐后分别服用ATS 40 mL、80 mL和120 mL,运动15分钟或不运动15分钟。结果表明,餐后BrAC低于餐前。饮用ATS后进行体育锻炼的受试者BrAC低于不进行体育锻炼的受试者。采用多元回归分析(R^2=0.56),体重较高、饮酒、饮食和体育锻炼频率较高的受试者BrAC显著降低。我们的发现显示了BrAC和ATS体积之间的体积依赖关系。此外,餐后服用ATS并进行体育锻炼与降低BrAC有关。
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