Transcatheter Closure of Atrial Septal Defect with Amplatzer Device in Adolescence and Adults: Short Term Results: MCVTC Experience

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Abstract

Introduction: Atrial septal defect (ASD) is one of the common congenital heart diseases accounting for 8% to 10% of total congenital heart disease at birth and one of the most common diseases in adulthood. Ostium Secundum (OS) ASD has been successfully closed surgically for over several decades. But even though the results are better, it is associated with discomfort, morbidity, and a thoracotomy scar. Transcatheter closure in these patients has advanced rapidly in recent years and represents a growing field in invasive cardiology. Methods: This prospective study was conducted at Manmohan cardiothoracic vascular and transplant center, Maharajgung, Kathmandu, Nepal. Fifty-two (52) patients with a diagnosis of OS ASD assessed for device closure. Patients underwent transthoracic and trans oesophageal echocardiography for the defect location, size, number, and associated anomalies. All patients with OS ASD fulfilling the inclusion criteria enrolled for device closure. The procedure conducted under fluoroscopy and transesophageal guidance. The cases were followed up at 3 and 6 months, reassessed clinically and by echocardiography for any complications. Results: The patients with ASD who enrolled in this study belonged to the age group of 14 to 63 years. The device closure attempted in 46 patients, and the remaining six patients excluded from the procedure due to unsuitable anatomy after GA guided TEE done. Among 46 patients, 44 (95%) had successful device closure. The mean age of the patient was 35.7+ 10 and 33 (71.7%) female, with 13 (28.3%) males. Conclusions: The transcatheter device closure of ASD in adolescents and adults has a high success rate with fewer complications and found to be safely documented during immediate and short term follow up. However, long terms follow up is required to conclude it.
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用Amplatzer装置经导管封闭青少年和成人房间隔缺损:短期结果:MCVTC经验
房间隔缺损(Atrial septal缺损,ASD)是一种常见的先天性心脏病,占出生时先天性心脏病总数的8% ~ 10%,是成年后最常见的疾病之一。在过去的几十年里,ASD已经成功地通过手术关闭了第二口(OS)。但即使效果更好,它也与不适、发病率和开胸疤痕有关。近年来,这些患者的经导管闭合治疗进展迅速,是侵入性心脏病学中一个不断发展的领域。方法:这项前瞻性研究在尼泊尔加德满都Maharajgung的曼莫汉心胸血管和移植中心进行。对52例诊断为OS ASD的患者进行器械关闭评估。患者接受经胸和经食管超声心动图检查缺损的位置、大小、数量和相关异常。所有符合纳入标准的OS ASD患者入组进行器械关闭。该手术在透视和经食管指导下进行。随访3个月和6个月,重新评估临床和超声心动图是否有并发症。结果:本研究纳入的ASD患者年龄在14 ~ 63岁之间。46例患者尝试闭合装置,其余6例患者在GA引导TEE完成后因解剖结构不合适而被排除。46例患者中,44例(95%)成功关闭装置。患者平均年龄35.7+ 10岁,女性33岁(71.7%),男性13岁(28.3%)。结论:经导管装置封堵青少年和成人ASD成功率高,并发症少,经即时和短期随访记录安全。然而,结案需要长期的后续工作。
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