Impact of Transcranial Direct Current Stimulation on Patients With Parkinson’s disease: A Report of 2 Cases

Abstract

Introduction: The motor function is associated with the activity of both the motor and prefrontal cortices. The efficacy of transcranial direct current stimulation (tDCS) over specific brain cortices has been examined in many psychiatric and neurologic disorders. This study aims to report the tDCS effects on two females of advanced age with idiopathic Parkinson’s disease (PD). Case Presentation: We considered 50-minute sessions of bilateral primary motor cortices and left dorsolateral prefrontal cortex (DLPFC) anodal stimulation using tDCS with passive stretching exercises simultaneously for a total of 20 sessions in 7 weeks. Clinical signs and electroencephalography (EEG) waveform were assessed at distinct times. Both of the two patients showed improved motor function for a short time. EEG changes to some extent concerned clinical states. Conclusion: It seems that tDCS can be an auxiliary treatment for motor dysfunction in PD; however, further studies must be carried out to prove the claim.